Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The list features several ineffective passwords that have, for some reason, long maintained their hold among internet users.
周边环境：这栋房屋位于Kenwood社区，该社区分布着19至20世纪的都铎式、地中海式、维多利亚式和殖民地风格的建筑，在明尼阿波利斯市湖链区(Chain of Lakes)的锡达湖(Cedar Lake)与群岛湖(Lake of the Isles)之间。这里的道路蜿蜒曲折；人行道两边排列着枫树和白蜡树。据该房源的代理说，该社区许多较老的房屋都已翻修过，而近30年内建造的房屋都推倒重建了。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
3. Kraft. Brand love: -10% / Rank: 11
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
“As we work to keep and attract more young professionals and job creators, we appreciate every young person who is engaged and invested in our state.”
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
“气候变化也许是我们这代人的重大挑战，”美国国家航空航天局(NASA)地球科学部主任迈克尔·H·弗莱利赫(Michael H. Freilich)说，他的部门是跟踪全球气温的机构之一。
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Average age: 36
3所在这份榜单上叱咤多年的重量级学府——哈佛商学院(HBS)、伦敦商学院(LBS)和麻省理工斯隆管理学院(MIT Sloan School of Management)的排名下滑。哈佛商学院的排名下降两个位次，今年排在第四，这是这所位于波士顿的学府9年来首次跌出前三甲。伦敦商学院下滑3个位次，排在第六，为14年来最低。麻省理工斯隆管理学院的排名下滑至第13位，为10年来首次跌出前10。
Don't mistake the lack of a late flurry for an uneventful deadline:
Trends and targets in antiviral phototherapy
"When the actual dependency ratio of pension insurance gets down to three to one, the payment cannot be lower than 17 percent. If it drops to two to one ratio, it means that everyone is going to pay 25 percent. The financial burden gets heavier when the dependency ratio gets lower. The restructuring of pension system must be finalized in two years." Yang said.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
This year, China will further enhance international cooperation in fighting corruption, said a statement adopted at the second plenary session of the 19th CPC Central Commission for Discipline Inspection.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Stevens会演唱电影《以你的名字呼唤我》中《Mystery of Love》，以及Bernal, LaFourcade和 Miguel会合唱《寻梦环游记》中的歌曲《Remember Me》。
Investigators have arrested one youth and one 18-year-old in connection to the July 9th shooting.
ACE2 as a potential therapeutic target for pandemic COVID-19
Google and Amazon rank second and third respectively.
“If they, say, delay a customary process for Korean imports and take other retaliatory measures on Korean products, there is nothing Korea can do about it,” he said.
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
PBS' 'Vietnam War' series receives a special award.
Celebritites always seem to have a better life than the rest of us;nicer house,cooler cars and even cuter children.Just look at these pictures of Shiloh Jolie-
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Rich blessings for health and longevity is my special wish for you in the coming year.
联系方式：Kathy Michalove, Seaboard Properties, (860) 535-8364; seaboardpropertiesre.com
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
This includes McKinsey, the consultancy that kick-started its secretive leadership election process in October with a gathering of more than 500 senior partners at the Grosvenor House Hotel in London. The next stage involves the firm’s 550 senior partners voting on a shortlist of candidates to replace Dominic Barton — the incumbent since 2009 — in January, followed by a run-off between the two most popular candidates in February.
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
President Barack Obama won re-election to a second term in the White House on Tuesday, television networks projected, beating Republican challenger Mitt Romney after a long and bitter campaign。
Influenza neuraminidase: A druggable target for natural products
9. CO2 in the Earth's atmosphere passes 400 parts per million
Dua Lipa, 'Dua Lipa'
A fallen tree blocks a street in Washington, DC, on Tuesday.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
"China is Australia's most valuable tourism market, with the potential to be worth more than $13 billion by 2020."
One key thing the best bosses seem to have in common is that they are all consummate problem solvers. They can not only spot them, but brainstorm successful and innovative ways to fix them。
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
We will improve mechanisms that give incentives and allow for and address mistakes so as to support those who are dedicated to their work and stand behind those who live up to their responsibilities. Every one of us in government must take an active approach to our work and have the courage to tackle the toughest problems, we must work closely with the people, using concrete action to make progress in development, and using genuine hard work to realize a bright future.
Japan, ranked No. 5 overall, is the top performing Asian country. It ranks No. 5 in Movers and No. 1 as the most forward-looking country.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
May the beauty and joy of New Year remain with you throughout the new year!
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
"Students are not suited for starting businesses on their own," said Zhang, adding that vocational students are more eager to start businesses than university undergraduates.
Inhibition of SARS coronavirus helicase by bismuth complexes
The drama got 7.2 points on Douban, receiving criticism for having too much romance and too few of Zhou's struggles.
As the younger generation begins to frown on Bond’s chauvinistic attitudes and unhealthy lifestyle in the era of political correctness, Horowitz has introduced a cast of new characters who will point out the error of his ways.
The United States ranks No. 7 overall. The country with the largest economy in the world is also considered the most powerful. It ranks No. 3 in Entrepreneurship and No. 3 in Cultural Influence, as well.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
《自己土地上的陌生人： 美国右翼的愤怒与哀悼》(Strangers in Their Own Land: Anger and Mourning on the American Right)一书的作者阿莉?罗素?霍克希尔德(Arlie Russell Hochschild)对路易斯安那州的农村社区进行了四年的研究，她认为那里“深藏着”一种失去机会的感觉。
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
‘Law & Order: SVU’ This NBC ripped-from-the-soap-opera perils of Olivia (Mariska Hargitay) — psychopath rapist-stalker, tortured love affair, new baby — that took up so much air last season finally died down, and this season, the show’s 16th, the detectives got back to sex crimes à clef, including a Ray Rice-inspired episode about a star sportscaster who was seen on a surveillance camera punching the lights out of his wife.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Rated 6.4 points out of 10 on the review website, some users said the drama focused too much on romance.
No one since Michael Haneke has enjoyed cinematically dissecting social conventions as much as Greek film-maker Yorgos Lanthimos. His The Lobster took Cannes by storm two years ago with its scathing look at a society that turns adults into animals if they cannot find a romantic partner within 45 days – it was our world but pushed toward the outermost limits of groupthink and conformity. Now he’s back with The Killing of a Sacred Deer, a domestic thriller about a surgeon (Colin Farrell) and his wife (Nicole Kidman), also a doctor, who befriends a fatherless teen named Martin. The boy seems determined to expose the family’s secrets and unmask a terrible trauma from their past. Is this film about how domestic (and perhaps societal) tranquility sometimes depends on shared, agreed-upon lies? Either way, prepare to be unnerved. Released November 9 in Denmark, November 16 in Russia and November 30 in China's Hong Kong. (Credit: A24)
Over the next few years, large residential buildings will have to comply with Local Law 87, which requires them to audit energy usage and keep systems running at peak efficiency. Residential buildings are the city’s largest source of greenhouse gas emissions, accounting for 37 percent of the total. “The one hot-button topic is energy. How do buildings become more energy efficient?” said Dan Wurtzel, the president of FirstService Residential New York, which manages more than 500 properties. “If a third of your operating budget is related to energy and you can now reduce that cost, you can take pressure off the need for a maintenance increase.”
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Du Pont called himself “the Golden Eagle” and had a distinctive, eagle-like profile. The designers aimed to capture that profile while not creating a carbon copy of the real du Pont.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
May the joy of New Year be with you throughout the year.愿新年的快乐一年四季常在。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Nirvana in Fire unexpectedly achieved a tremendous success, rising like a star among the TV dramas in the fall of 2015. Also adapted from an online novel of the same name written by Hai Yan, the adaptation for the first time found its way on the screen in September 2015. Staring Hu Ge and Liu Tao, the series shows a talented military strategist endeavoring to clear his name through continuous fights. The fictional characters and dynasty let the adaptation smartly avoid being criticized for not sticking to historical accuracy. And the drama`s delicate internal settings and impeccable storyline were highly praised by the audiences.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
简而言之，C型人格的人是完美主义者， 始终如一，永远不会违反规则。 与A型人格的人不同的是，C型人会花时间处理细节，经常反复检查工作是否准确。他们往往是深思熟虑的人，喜欢了解自己工作和生活的每一个细节。
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
It is the first time since 2001 that an athlete other than Mayweather Jnr or golfer Tiger Woods topped the earning league.
By the end of 2015, Shanghai's population of migrant residents had decreased to 9.8 million, comprising 40.6 percent of the city's roughly 24 million permanent residents, according to statistics released by the Shanghai Municipal Statistics Bureau on Monday.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
The CPI rose by 2 percent.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
位居榜单第三的是史蒂夫·卡瑞尔（Steve Carell）。《卑鄙的我2》（Despicable Me 2）在今年大获成功，斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房，该系列第三部《小黄人》（Minions）也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》（The Way Way Back）和《超级魔术师》（The Incredible Burt Wonderstone）。后一部影片的票房虽未能赚回制作成本，但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。
Arlie Russell Hochschild, the author of “Strangers in Their Own Land: Anger and Mourning on the American Right,” describes a feeling of lost opportunity as the “deep story” of the rural Louisiana communities she spent four years studying.
That Teach First was able to overcome such conditioning is testament to the power of a scheme that has become both a rival to UK private sector recruiters and a finishing school for them.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
The base hopes to keep up public awareness of pandas and the necessity of conservation of their natural habitats while Increasing the wild population by reintroducing individuals into areas in China where populations have declined.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
The United States ranks No. 7 overall. The country with the largest economy in the world is also considered the most powerful. It ranks No. 3 in Entrepreneurship and No. 3 in Cultural Influence, as well.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
In a televised debate on Monday night, Mr Wilders called on the Netherlands to expel the Turkish ambassador.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Her piece, titled “Back to Mother Nature," depicts an elaborate water-cleaning machine. Zhang worked with a team of artists at Google to animate her drawing.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Blue skies will not be, and should not be, a luxury.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
3 . 《歌剧魅影》（ T h e Phantom of the Opera ）是 由安德鲁·韦伯（Andrew Webber）作曲的著名音乐剧，剧中的男主人公“魅影”（Phantom）的右脸上戴着一副面具。
STEP 5: GET RID of most of your friends
A Datafolha polling group survey published in the Folha de S. Paulo newspaper showed that at Saturday's Brazil versus Chile match, 67 percent of attendees classified themselves as white and 90 percent came from Brazil's top two economic classes, which represent about 15 percent of the country's population.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Staff numbers at insurance agencies also rose by 936,200 to a total of more than 5.6m people.
So what does 2015 portend? Here are some educated guesses.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Beauty and Evolution
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Those falls came despite a rise in insurance premium income of 37.3 per cent year-on-year to Rmb1.88tn, while total assets reached Rmb14.27tn, up 15.4 per cent.
For many Western whites, opportunities for achieved identity — the top of the hill — seem unattainable. So their ascribed identity — their whiteness — feels more important than ever.
Length-scale dependence of protein hydration-shell density
“…was asked ttell the interviewer a little about herself, and didn’t have anything tsay.”
Summly的一个早期版本──Trimit，于2011年7月出现在了苹果app store“新品推荐”栏目中。正是在这里，它被极具影响力的硅谷《科技博客》(TechCrunch)所关注，并迅速引起了李嘉诚的投资集团的注意。当达洛伊西奥收到李嘉诚的维港投资(Horizons Ventures)发来的电子邮件时，他只有15岁，并且基本没让什么人知道他所做的事情。在那之前，他从未与科技领域内的任何人物见过面，而他在Trimit的登记信息中也只是粗略形容自己是“伦敦的一家科技公司”。仅靠这一信息，谁也不会想到这家公司的管理和技术团队──事实上，它的全部职员──竟然是住在郊区卧室里的一个连车都不能开的小孩。
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
The Irish. They sing, dance, drink and sing some more. The lads were singing lullabies to a little baby in Bordeaux to try and get it to go to sleep.
Big Little Lies
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The relatively stable global outlook must continue if 2014 is to be the kind of economic year Americans have been hoping for throughout the recovery.
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